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Clinical Trials (Phases I–IV)
Design, endpoints, enrollment, interim reads, and post‑market surveillance.
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Latest in Clinical Trials (Phases I–IV)
First Tracks Biotherapeutics to Announce Top-Line Data from Cohort 1 of Phase 1b Trial of ANB033, a CD122 antagonist, in Celiac Disease on Oct. 12, 2026
11+ hour, 29+ min ago (184+ words) SAN DIEGO, Oct. 11, 2026 (GLOBE NEWSWIRE) -- First Tracks Biotherapeutics, Inc. (Nasdaq: TRAX), a clinical-stage biotechnology company advancing antibody therapeutics that modulate immune pathways implicated in autoimmune and inflammatory diseases, will host an investor call and live webcast to review top-line data…...
Phase 3 topline REVEAL-1 results for elegrobart for TED
11+ hour, 13+ min ago (349+ words) Viridian Therapeutics issued a press release that announced the positive elegrobart topline results from the phase 3 REVEAL-1 clinical trial in which the drug was evaluated to treat active thyroid eye disease (TED). The trial tested the effects of 2 regimens of…...
Swiss pharma giant Roche presents positive data on eye disease drug
16+ hour, 29+ min ago (187+ words) The data show that the treatment delivers sustained improvements in vision and reduces retinal swelling over a 52-week period. This content was published on Sep 19, 2025 Switzerland’s new process to speed up patient access to the latest drugs hit its first…...
Multitarget Antibodies Explored for Severe Nasal Polyps
17+ hour, 25+ min ago (416+ words) ANTIBODIES DESIGNED to recognise more than one target are being explored as potential treatments for chronic rhinosinusitis with nasal polyps, according to a review examining the rationale for broader inflammatory pathway inhibition. The authors consider whether dual- and multispecific antibodies…...
HS Treatment Selection and Comorbidity Screening: Practical Tips With Jennifer Hsiao, MD
18+ hour, 51+ min ago (299+ words) Patient preference, comorbidities, and access guide HS treatment selection, Jennifer Hsiao, MD, said at Fall Clinical. With 3 FDA-approved biologics now available for hidradenitis suppurativa (HS), treatment selection comes down to age, patient preference, comorbidities, and access, Jennifer Hsiao, MD, said…...
Phio Pharmaceuticals Highlights 85% Response Rate as PH-762 Nears Phase 2b
19+ hour, 27+ min ago (572+ words) Posted by Defense World Staff on Oct 11th, 2026 The company’s approach centers on INTASYL, a self-delivering short interfering RNA platform designed to silence specific genes. PH-762 targets PD-1, a protein that can inhibit immune-cell activity. By temporarily reducing PD-1 production within…...
Epigenetic Drug Valemetostat Shows Dual Action Against HTLV-1 Eye Inflammation
19+ hour, 6+ min ago (47+ words) A new study shows that the dual EZH1/2 inhibitor valemetostat counteracts HTLV-1-induced epigenetic changes in retinal cells and suppresses viral transcription and inflammatory signaling in a model-dependent manner. News Source: Juliet Wilcox. (October 11, 2026). Epigenetic Drug Valemetostat Shows Dual Action Against…...
Roche's vamikibart shows sustained vision improvement in uveitic macular edema, FDA decision expected by July 2027
1+ day, 9+ hour ago (227+ words) Roche announced positive one-year Phase III trial results for vamikibart, an investigational non-steroid treatment for uveitic macular edema (UME), showing sustained vision improvement and reduced macular swelling. The FDA has accepted Roche's Biologics License Application for vamikibart, with a decision…...
Hidradenitis Suppurativa: Immune Pathways and Evolving Interventions
1+ day, 6+ hour ago (466+ words) HS is frequently misdiagnosed for 7 to 10 years because its symptoms resemble conditions like inflamed epidermal cysts, nodulocystic acne, and furuncles. Table 1. Hurley Staging for Hidradenitis Suppurativa1 Solitary or multiple isolated cysts/abscesses. No scarring or sinus tracts. HS also profoundly affects…...
Managing Treatment Expectations in Hidradenitis Suppurativa: What to Tell Patients Before Starting Therapy
1+ day, 6+ hour ago (229+ words) Jennifer Hsiao, MD, explains how defining HS treatment response improves adherence and success. Hsiao, a professor of dermatology at the University of Southern California, where she codirects an HS specialty clinic, drew a contrast with psoriasis and eczema. In those…...