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Discovery & Preclinical
Targets, assays, animal models, and early safety/tox studies before human trials.
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Latest in Discovery & Preclinical
New forensic science and protective medicine facility opens in Wauwatosa
1+ day, 17+ hour ago (148+ words) WAUWATOSA — Gov. Tony Evers and Milwaukee County Executive David Crowley joined local leaders Friday to celebrate the opening of a new forensic science and protective medicine facility. The four-story facility houses Wisconsin’s Milwaukee Crime Lab, the Milwaukee County Medical Examiner’s…...
Nerve-Stimulating Device for Cancer Wasting Enters First Human Trial
1+ day, 19+ hour ago (590+ words) OnVagus has received approval to begin the first human trial of its noninvasive vagus nerve-stimulation device for cancer-related wasting at MD Anderson Cancer Center....
Hidden Enzyme in B Cells Emerges as a Master Switch for Allergic Asthma
3+ day, 53+ min ago (110+ words) Deleting the Ssu72 phosphatase specifically in B cells sharply reduces IgE and IgG1 production and lung inflammation in a mouse model of allergic asthma, revealing a novel intracellular regulator of allergic antibody responses. Subject of Research: The role of the B cell-intrinsic…...
2026 AHA CME Symposium - Inflammation as a Therapeutic Target in ASCVD
5+ day, 16+ hour ago (135+ words) CMEPlanet PRLog 2026 AHA CME Symposium - Inflammation as a Therapeutic Target in ASCVD - Describe the role of the IL-1βgIL-6gCRP inflammatory pathway in atherosclerotic plaque progression and rupture, and explain the clinical evidence supporting hsCRP as an independent predictor of recurrent MACE in…...
Peng Gao receives NIH New Innovator Award for research measuring chemical exposure in blood and tissues
5+ day, 18+ hour ago (349+ words) Peng Gao, assistant professor of environmental health and exposomics at Harvard T.H. Chan School of Public Health, was awarded an NIH Director’s New Innovator Award from the National Institutes of Health’s High-Risk, High-Reward Research program. The award was one of 57 new…...
Chemical Insights’ research to make an impact at The International Society of Exposure Science Annual Meeting
6+ day, 9+ hour ago (138+ words) Credit: UL Research Institutes UL Research Institutes’ Chemical Insights’ scientists will share their latest information on chemical and exposure safety at the 2026 International Society of Exposure Science (ISES) Annual Meeting in Vancouver, Canada. Chemical Insights is hosting a symposium, five…...
Gut Microbes Prime Regulatory B Cells That Shape Cancer Immunotherapy
1+ week, 2+ day ago (618+ words) Checkpoint inhibitors have transformed the treatment of advanced cancers, yet only a minority of patients derive lasting benefit, and many develop immune-related adverse events that force treatment to stop. A review published in Cancer Immunology, Immunotherapy by Akshay J. Patel and…...
Gut bacterial compound worsens brain injury after stroke, study suggests
1+ week, 3+ day ago (12+ words) Medical Xpress...
Gut bacterial metabolite worsens brain damage after stroke, study finds
1+ week, 3+ day ago (449+ words) News-Medical Be the first to rate this article Gut bacterial metabolite worsens brain damage after stroke, study finds Researchers at LMU have discovered how a metabolite produced by gut bacteria can influence brain damage after stroke. How much damage a…...
How Gut Bacteria Can Shape the Brain???s Response to Stroke
1+ week, 3+ day ago (41+ words) How Gut Bacteria Can Shape the Brain’s Response to Stroke | Newswise Newswise How Gut Bacteria Can Shape the Brainâs Response to Stroke Researchers at LMU have discovered how a metabolite produced by gut bacteria can influence brain damage after…...